Tirzepatide is a drug that is under development for the treatment of obesity and type 2 diabetes. It is a combination of two drugs: a long-acting form of exenatide, a medication that is already used to treat type 2 diabetes, and a GLP-1 agonist called liraglutide.
Exenatide and liraglutide are both agonists of a hormone called glucagon-like peptide-1 (GLP-1), which is produced in the gut and plays a role in regulating appetite and glucose metabolism. By activating GLP-1 receptors, these drugs can help to reduce food intake, increase insulin secretion, and improve glycemic control.
The combination of exenatide and liraglutide in tirzepatide is thought to enhance the effects of these medications on weight loss and glucose control. In clinical trials, tirzepatide has been shown to be effective at reducing body weight and improving markers of metabolic health, such as HbA1c and fasting plasma glucose. However, tirzepatide is still in development and has not yet been approved for use by regulatory agencies.
How do you take Tirzepatide?
Tirzepatide is administered as a subcutaneous injection, which means that it is injected into the fatty tissue just under the skin. The injection can be given in the abdomen, thigh, or upper arm. It is typically given once daily at the same time each day. The recommended starting dose is 15 mg once daily, which can be increased to 30 mg once daily if needed. The dosage should be adjusted based on the patient's response to treatment and the presence of any side effects.
It is important to follow the instructions provided by a healthcare provider when administering tirzepatide or any other medication. If you have any questions about how to give the injection or about the dosing schedule, you should consult with your healthcare provider.
What are the side effect of Tirzepatide?
Tirzepatide is a medication that is still in development, so the full range of potential side effects is not yet known. However, based on the known side effects of the individual components of tirzepatide (exenatide and liraglutide), some potential side effects of the drug may include:
- Abdominal pain
It is important to note that not everyone who takes tirzepatide will experience side effects. In clinical trials, the most common side effects of tirzepatide were nausea and vomiting, but these effects were generally mild to moderate in severity and resolved on their own over time.
If you experience any side effects while taking tirzepatide, you should inform your healthcare provider. They can advise you on how to manage any side effects and determine whether the medication is still appropriate for you.